Melanotan 2 · Dosing & maths

Melanotan 2 dosage: what the research used

Reviewed 22 October 2026 · How we research

This page collects the doses reported in published Melanotan 2 research and works through the reconstitution maths for common vial sizes. It does not recommend any dose.

Doses used in published research

The 1990s phase 1 studies used subcutaneous doses of 0.01–0.025 mg/kg on alternate days for a limited period under supervision. No dose is approved.

Melanotan 2 reconstitution table

Syringe units (U-100: 100 units = 1 mL) needed for a given amount, by vial size and water volume:

VialWaterConcentration250 µg500 µg1 mg
10 mg1 mL10 mg/mL2.5 units5 units10 units
10 mg2 mL5 mg/mL5 units10 units20 units
10 mg3 mL3.333 mg/mL7.5 units15 units30 units

Melanotan 2 reconstitution calculator

Concentration—
Volume to draw—
Syringe units (U-100)—
Measurements per vial—

Arithmetic aid for laboratory reconstitution. It does not recommend any amount for any use.

Handling and storage

Reconstitute with bacteriostatic water, adding it slowly down the vial wall and swirling rather than shaking — see the reconstitution guide. Once mixed, refrigerate at 2–8 °C; unmixed lyophilised powder keeps longest frozen (storage guide). Converting between units, mL and mg is covered in syringe units explained.

Melanotan 2 dosing FAQs

How much bacteriostatic water for a 10 mg Melanotan 2 vial?

There is no fixed amount — the volume sets the concentration. Adding 2 mL to a 10 mg vial gives 5 mg/mL; 1 mL gives 10 mg/mL, 2 mL gives 5 mg/mL, 3 mL gives 3.333 mg/mL.

How many units is 250 µg of Melanotan 2?

At 5 mg/mL (10 mg in 2 mL), 250 µg is 0.05 mL, or 5 units on a U-100 syringe. A different water volume changes this — use the calculator above.

Is there an approved Melanotan 2 dose?

See the published trial doses above. Any human use of a licensed medicine should follow its prescribing information and a prescriber's advice.

What is a Melanotan 2 dosage chart?

A table showing how many syringe units a given amount takes at a given concentration. The reconstitution table on this page is one, calculated for 10 mg vials.