Blends

Wolverine Stack

Reviewed 22 October 2026 · How we research

Also known as: BPC-157/TB-500 blend, Wolverine blend, BPC TB

What is Wolverine stack?

The Wolverine stack — named after the fast-healing comic-book character — is the nickname for BPC-157 and TB-500 used together, usually as a single pre-mixed vial. The rationale is that the two peptides help repair through different routes: BPC-157 mainly through blood-vessel growth and fibroblast signalling, TB-500 through actin regulation and cell migration.

It is important to be clear about the evidence: there are no published studies on the combination itself. Everything known comes from the separate literature on each component.

How Wolverine stack works

See the individual pages for BPC-157 and TB-500. The theoretical case for combining them is complementarity: BPC-157 appears to act more locally on blood supply and tendon fibroblasts, while thymosin beta-4 acts more systemically on cell migration and inflammation.

A pre-mixed blend fixes the ratio. With a 1:1 vial, every measured amount contains equal parts of each peptide — you cannot adjust one without the other.

What the research shows

BPC-157: extensive rodent data on tendon, ligament, muscle and gut healing; no controlled human efficacy trials.
TB-500 / thymosin beta-4: rodent wound and heart repair data, plus human trials of the full-length protein in eye conditions.
No study has tested whether the combination performs better than either peptide alone.

Wolverine stack side effects

Combines the uncertainties of both peptides. Neither has long-term human safety data, and both are pro-angiogenic, which is a theoretical concern for anyone with an existing tumour.

UK legal status

Both components are unlicensed in the UK and sold for research only. Both are prohibited by WADA.

More detail, including current UK research-vial prices: Wolverine stack UK guide. For the doses used in published studies and the reconstitution maths: Wolverine stack dosing in the literature.

Wolverine stack: frequently asked questions

What is the Wolverine stack?

A combination of BPC-157 and TB-500, usually sold as a 1:1 pre-mixed vial, named for its intended use in tissue-repair research.

Is there research on BPC-157 and TB-500 together?

No. Each peptide has its own animal (and for Tβ4, some human) research, but the combination has not been studied.

How do you work out the dose from a blend vial?

Use the total peptide mass. A 10 mg (5+5) vial in 2 mL water is 5 mg/mL total — each component is 2.5 mg/mL.

Wolverine stack vs GLOW blend?

GLOW adds GHK-Cu to BPC-157 and TB-500. See the GLOW blend page.

References

Gwyer D, Wragg NM, Wilson SL. Cell Tissue Res. 2019;377:153–159 (BPC-157 review).
Goldstein AL, Hannappel E, Kleinman HK. Trends Mol Med. 2005;11:421–429 (thymosin β4 review).

Related compounds

Tissue repair